A 7-year-old girl presents with bilateral swelling of the mandible and maxilla. A radiograph shows bilateral multilocular radiolucent lesions of all four quadrants. Biopsy shows fibrous connective tissue with multinucleated giant cells. Serum chemistry is within normal limits. This patient has:

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Cherubism is characterized by bilateral swelling of the mandible and maxilla, with radiographs showing multilocular radiolucent lesions. The biopsy findings of fibrous connective tissue with multinucleated giant cells are also consistent with cherubism. Normal serum chemistry helps rule out hyperparathyroidism, which can present with similar bone changes but is typically associated with abnormal calcium or phosphorus levels.

A 7-Year-Old Girl Presents with Bilateral Swelling of the Mandible