In cases of persistent pulmonary hypertension of a newborn, what mode of ventilation maintains the same mean airway pressure and improves oxygenation and ventilation the fastest

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High-frequency oscillatory ventilation (HFOV) maintains a constant mean airway pressure (MAP) while delivering rapid, small tidal volumes. This mode of ventilation has been shown to improve oxygenation and ventilation quickly in cases of persistent pulmonary hypertension of the newborn (PPHN). It is also less injurious to the lungs compared to other modes of ventilation, such as conventional mechanical ventilation. While extracorporeal membrane oxygenation (ECMO) may be necessary in severe cases, HFOV is typically tried first as it is less invasive. Controlled mandatory ventilation (CMV) and high-frequency jet ventilation (HFJV) may not provide the necessary MAP and may be ineffective in improving oxygenation and ventilation in infants with PPHN.

In Cases of Persistent Pulmonary Hypertension of a Newborn, What