A maternal serum alpha-fetoprotein (AFP) test indicates an elevated level. It is repeated and again is reported as higher than normal. What would be the next step in the assessment sequence to determine the well-being of the fetus?
A) Percutaneous umbilical blood sampling (PUBS)
B) Ultrasound for fetal anomalies
C) Biophysical profile (BPP) for fetal well-being
D) Amniocentesis for genetic anomalies

Question

Quizplus · Accepted Answer

An elevated maternal serum AFP level can indicate a neural tube defect or other fetal anomalies. The next step would be to perform an ultrasound to visualize the fetus and assess for any structural abnormalities. This would help determine the well-being of the fetus and guide further diagnostic testing if necessary. PUBS and amniocentesis would be reserved for more invasive testing if abnormalities are found on the ultrasound or if there are other risk factors present. A BPP may also be performed, but the ultrasound for fetal anomalies would be the first step.

A Maternal Serum Alpha-Fetoprotein (AFP) Test Indicates an Elevated Level