Antimicrobial susceptibility is hard to control because many of the same species of organisms have a varied susceptibility to particular antibiotics.To reduce this variation,Clinical and Laboratory Standards Institute (CLSI)guidelines recommend the following:

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Specific ATCC strains of control organisms are recommended by CLSI.There is too much variation in organisms isolated from patients to use as quality control organisms.Hospital laboratories trying to share strains would find this a cumbersome process for routine quality control.CDC does not store routine strains of microbes for quality control testing.

Antimicrobial Susceptibility Is Hard to Control Because Many of the Same