The original source for the principles of codes of ethics for research on human subjects was developed out of

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The principles of codes of ethics for research on human subjects were developed in response to the horrific experiments that were conducted on human subjects during World War II, particularly at the Nuremberg Trials of Nazi war crimes in 1946-47. The Nuremberg Code was developed as a set of ethical guidelines for medical research involving human subjects and laid the foundation for modern codes of ethics for research on human subjects.

The Original Source for the Principles of Codes of Ethics