The nurse administers sulfamethoxazole and trimethoprim (Bactrim)for a desirable patient response derived from the combination of agents.Which type of medication effect does the nurse anticipate?

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The nurse anticipates a synergistic effect because the two antibiotics,sulfamethoxazole and trimethoprim,work better in combination than either agent works alone.Drug tolerance means that a larger dose of medication is needed to produce the same therapeutic effect over time.Drug dependence is psychological or physical.The patient takes the medication for an effect other than the therapeutic effect,resulting in psychological dependence.Physical dependence involves physiological adaptation to the medication that results in severe adverse effects if withdrawn abruptly.A subtherapeutic effect is less than therapeutic; the therapy treats the disorder inadequately.

The Nurse Administers Sulfamethoxazole and Trimethoprim (Bactrim)for a Desirable Patient