The induction phase of a cell-mediated immune response includes which of the following events? A)CD4⁺ T cell secretion of interferon-$\gamma$ leading to macrophage activation B)CD8⁺ T cell lysis of a virally infected cell C)Clonal expansion of CD8⁺ T cells within a lymph node D)Migration of CD4⁺ effector T cells from blood vessels into a tissue site of infection E)Migration of a naive CD4⁺ T cell from the thymic medulla into the circulation

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Quizplus · Accepted Answer

The induction phase of cell-mediated immune responses occurs in lymphoid tissues and includes antigen presentation to naive T cells,leading to clonal expansion and differentiation of those T cells into effector cells.Migration into infection sites and interferon-$\gamma$ secretion by CD4⁺ helper T cells,as well as target cell killing by CD8⁺CTL,are part of the effector phases of cell-mediated immune responses.Naive T cell migration out of the thymus is the last step in T cell maturation and occurs regardless of the presence of antigen.

The Induction Phase of a Cell-Mediated Immune Response Includes Which γ\gammaγ

The Induction Phase of a Cell-Mediated Immune Response Includes Which $\gamma$