Which of the following molecules is involved in the principal mechanism by which the immune system kills tumor cells?

Question

Quizplus · Accepted Answer

Cytolytic T lymphocyte (CTL)killing of tumor cells is the principal known mechanism for tumor immunity in vivo.This requires class I MHC expression by the tumor cells.In addition,natural killer cells (NK cells)can kill tumor cells that lack class I MHC.CTL and NK cells employ the same mechanism to kill tumor cells,which depends on perforin and granzyme B release from cytoplasmic granules.Although antibodies (e.g. ,IgG)and complement can kill tumor cells in vitro and tumor-specific antibodies can be detected in patients,it is not known if Ig or complement plays a significant role in tumor immunity in vivo.TGF-$\gamma$ (transforming growth factor-F1F1F1S1?F1F1F10)is an immunoregulatory cytokine produced by T cells and other cell types.TGF-$\beta$ does not kill tumor cells.Interleukin-2 has been used in protocols to treat certain tumors,but its effect is indirect and it does not directly kill tumor cells.

Which of the Following Molecules Is Involved in the Principal γ\gammaγ

Which of the Following Molecules Is Involved in the Principal $\gamma$