A 14-year-old boy is brought to the pediatrician's office in mid summer because of an itchy,blistering rash on his calves and forearms.The rash developed 24 hours after he returned from a weekend Boy Scout camping trip.The pediatrician suspects the lesion is caused by poison ivy.If the doctor is correct,which one of the following is NOT a prominent component in the immunologic mechanisms causing the skin lesions?

Question

Quizplus · Accepted Answer

Poison ivy rash is a form of contact dermatitis in which there is a delayed-type hypersensitivity (DTH)reaction.The patient's vesicular dermatitis was evoked by his repeated exposure to urushiol,the antigenic component of poison ivy.Endothelial adhesion molecules and chemokines mediate the recruitment of previously sensitized CD4⁺ T cells of the T_H1 subset and CD8⁺ T cells,which secrete cytokines such as interferon-F1F1F1S1F1F1F10 and activate macropha-ges.Activated macrophages release enzymes and reactive oxygen intermediates that damage cellular tissue.IgE-coated mast cells are involved in immediate hypersensitivity reactions,not DTH reactions.

A 14-Year-Old Boy Is Brought to the Pediatrician's Office in Mid