A client with advanced cancer is being treated with intravenous mithramycin (Mithracin).Which clinical manifestation indicates that the treatment is effective?

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Quizplus · Accepted Answer

Mithramycin is used to treat hypercalcemia,which is seen most often in oncology clients who have bone metastases.Hypercalcemia reduces excitable membrane activity,causing decreased intestinal motility.Return of intestinal motility is an indication that serum calcium levels are decreasing.Mithramycin has no direct effect on serum sodium levels or urine output.The pulse rate most likely would be rapid and irregular with hypercalcemia and would normalize as calcium levels return to normal.

A Client with Advanced Cancer Is Being Treated with Intravenous