Proteolytic enzymes should not be used to screen for antibodies because:
A)the reagent is too expensive for routine use.
B)clinically insignificant antibodies are enhanced.
C)red cells must be treated with enzymes first,which makes this technique impractical.
D)some antigens are destroyed by enzymes,which would cause the antibodies to be missed.

Question

Quizplus · Accepted Answer

Proteolytic enzymes destroy some antigens in the Duffy and MNS system.Antibody screens using enzymes would not detect antibodies to these antigens.

Proteolytic Enzymes Should Not Be Used to Screen for Antibodies