An antibody screen on a patient with a prior history of transfusion was negative.The crossmatch was incompatible with 1 unit selected at AHG phase.The next step in the investigation would be to:
A)perform a prewarm procedure for crossmatching
B)perform a direct antiglobulin test on the incompatible unit.
C)redraw the patient and begin a new crossmatch.
D)crossmatch a new unit and discard the incompatible unit.

Question

Quizplus · Accepted Answer

The most likely reason for the incompatibility is that the blood unit has a positive direct antiglobulin test or the patient has developed an antibody to a low-frequency antibody.If the direct antiglobulin test is negative,testing the patient's serum against a selected cell panel of low-frequency antigen-positive cells should be performed.

An Antibody Screen on a Patient with a Prior History