Beneficial effects of glucocorticoids on $\beta$-adrenergic receptors include

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A very beneficial effect of glucocorticoids is their ability to restore responsiveness to $\beta$-adrenergic stimulation.This effect can be seen within 1-4 hours after intravenous administration of glucocorticoids and is the rationale for administering a bolus of steroid in status asthmaticus as part of acute treatment.Although steroid action is slow,the sooner glucocorticoids are given,the sooner the asthmatic begins to respond to $\beta$-adrenergic drugs,and supported ventilation may be avoided.Glucocorticoids enhance $\beta$-receptor stimulation by increasing the number and availability of $\beta$ receptors on the cell surfaces and by increasing affinity of the receptor for $\beta$ agonists.

Beneficial Effects of Glucocorticoids On β\betaβ -Adrenergic Receptors Include A)restoration of Responsiveness

Beneficial Effects of Glucocorticoids On $\beta$ -Adrenergic Receptors Include
A)restoration of Responsiveness