Individuals attempting to quit smoking using Nicotrol should be advised

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Individuals receiving nicotine replacement therapy should be informed that the replacement formulations contain active nicotine.If these replacement formulations are taken while still using tobacco products,potentially toxic concentrations of nicotine can occur in the blood.Individuals should stop smoking when initiating therapy.Transference of nicotine dependency from the tobacco product to the replacement product can occur.Use within a program of smoking cessation is encouraged to achieve complete withdrawal.In clinical trials,varenicline (Chantix)produced a 39% quit rate compared with 20% for bupropion and 11% for placebo after 12 weeks.In another study,Chantix produced quit rates of 44% and 49% at lower and higher doses of the drug compared with placebo at 12%.Chantix is administered in a 12-week-long treatment process that begins with a 1-week titration process.Nortriptyline is a tricyclic antidepressant approved by the U.S.Food and Drug Administration (FDA)to treat depression.It is not approved by the FDA for use as a smoking cessation aid;however,similar to bupropion,it is thought to have an effect on tobacco dependence because of its antidepressant mode of action.

Individuals Attempting to Quit Smoking Using Nicotrol Should Be Advised