What genome composition makes viruses most susceptible to destruction by prokaryotic restriction endonucleases?
A) dsDNA
B) ssDNA
C) dsRNA
D) ssRNA

Question

Quizplus · Accepted Answer

Prokaryotic restriction endonucleases recognize and cleave double-stranded DNA (dsDNA) at specific nucleotide sequences known as restriction sites. Therefore, viruses with a dsDNA genome composition are the most susceptible to destruction by prokaryotic restriction endonucleases. While some restriction enzymes can also cleave single-stranded DNA (ssDNA) and RNA molecules, dsDNA is generally the preferred substrate. Viruses with ssRNA or dsRNA genomes would not be susceptible to destruction by prokaryotic restriction endonucleases.

What Genome Composition Makes Viruses Most Susceptible to Destruction by Prokaryotic