Which of the following is a way to prevent attenuation and maintain virulence in a bacterium?
A) laboratory subculture
B) animal passage
C) polymerase chain reaction (PCR)
D) antibiotic therapy

Question

Quizplus · Accepted Answer

Animal passage involves infecting animals with the bacterium, allowing it to replicate and maintain its virulence. This method is used to prevent attenuation, which is the loss of virulence in the bacterium when it is cultured for too long in the laboratory. Laboratory subculture, PCR, and antibiotic therapy do not prevent attenuation and may even contribute to it.

Which of the Following Is a Way to Prevent Attenuation