The complete second signal for B cell activation requires which of the following interactions?

Question

Quizplus · Accepted Answer

All of the interactions listed (CD40-CD40L, cytokine-cytokine receptor, TH-B cell) are necessary for the complete second signal for B cell activation. CD40-CD40L interaction leads to increased expression of co-stimulatory molecules on B cells. Cytokine-cytokine receptor interaction (such as IL-4 to IL-4R) is necessary for B cell proliferation and differentiation. TH-B cell interaction is necessary for cognate recognition and activation of B cells by specific T helper cells.

The Complete Second Signal for B Cell Activation Requires Which