The arrangement of Class II MHC proteins in pairs or trimers enhances their stability.

Question

Quizplus · Accepted Answer

Class II MHC proteins are composed of two alpha and two beta chains that form a stable heterodimer. These heterodimers can further associate into pairs or trimers, which increases their stability and allows for a higher affinity for peptide binding. This arrangement also facilitates the presentation of antigen to T-cells. Therefore, the statement is true.

The Arrangement of Class II MHC Proteins in Pairs or Trimers