Anemia of chronic disease is characterized by:

Question

Quizplus · Accepted Answer

Anemia of chronic disease is caused by a block in iron release from macrophages, which results in decreased availability of iron for erythropoiesis. This occurs due to inflammation and cytokine stimulation, leading to increased hepcidin levels which target ferroportin, the protein responsible for iron release from macrophages. This results in functional iron deficiency and impaired erythropoiesis. A, B, and C are incorrect as they pertain to other types of anemia such as beta-thalassemia, iron-deficient anemia, and porphyria, respectively.

Anemia of Chronic Disease Is Characterized By