Select the best statement from the choices below to describe the pathogenesis of PNH.

Question

Quizplus · Accepted Answer

PNH is characterized by the deficiency of cell membrane proteins that regulate complement activation, specifically CD55 and CD59. This deficiency leads to uncontrolled complement activation and subsequent hemolysis of red blood cells. Option A describes the pathogenesis of cold agglutinin disease, option C describes the pathogenesis of hereditary spherocytosis, and option D describes the pathogenesis of autoimmune hemolytic anemia.

Select the Best Statement from the Choices Below to Describe