Plasmodium falciparum infection is accompanied by a severe form of anemia due to what factor?

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Plasmodium falciparum infection causes destruction of red blood cells and high levels of parasitemia (number of parasites in the blood), which leads to severe anemia. While toxins are produced by P. falciparum, they are not the primary cause of anemia. The lack of spleen removal of infected cells may contribute to anemia, but it is not the main factor. P. falciparum does not produce exotoxins that affect host cell membranes.

Plasmodium Falciparum Infection Is Accompanied by a Severe Form of Anemia