The underlying cause of TTP is:

Name: The underlying cause of TTP is:
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Question

Quizplus · Accepted Answer

TTP is caused by deficiency or dysfunction of a protease called ADAMTS13, which normally cleaves von Willebrand factor (vWF) multimers. In its absence, the large vWF multimers lead to platelet adhesion and clot formation, resulting in microvascular thrombosis. This is not related to an unregulated coagulation cascade or overproduction of cryoprecipitate.

The Underlying Cause of TTP Is