A peripheral blood smear examination shows many WBCs with many blue-staining round inclusions present.There is thrombocytopenia with giant platelets present.What autosomal dominant disease is associated with these findings?

Question

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May-Hegglin anomaly is an autosomal dominant disorder that is characterized by large platelets, thrombocytopenia, and the presence of blue-staining round inclusions in neutrophils and monocytes. Alder-Reilly anomaly is associated with the presence of large, dark-staining granules in neutrophils and other cells. Chédiak-Higashi anomaly is characterized by the presence of large, abnormal lysosomal granules in cells and is associated with recurrent infections and neurologic dysfunction. Megaloblastic anemia is not associated with the findings described in the question.

A Peripheral Blood Smear Examination Shows Many WBCs with Many