The most striking finding in the peripheral blood in this disease is extreme and consistent thrombocytosis. Giant, bizarre platelet forms are present in the peripheral blood. Megakaryocytes and megakaryocyte fragments can be present. Abnormalities in platelet aggregation and adhesion are common. What is this disease?

Question

Quizplus · Accepted Answer

The extreme and consistent thrombocytosis along with the presence of giant, bizarre platelet forms in the peripheral blood is characteristic of essential thrombocythemia (ET), which is a myeloproliferative neoplasm. Megakaryocytes and megakaryocyte fragments can also be present in ET, further supporting this diagnosis. The other options (PV, CML, and mast cell disease) do not typically present with this pattern of thrombocytosis and abnormal platelet morphology.

The Most Striking Finding in the Peripheral Blood in This