A patient presents with a morphological smear examination revealing greater than 20% blasts with prominent granules and ++ Auer rods, MPO, and Sudan Black positive.A 25% monocyte count was seen in the peripheral smear.There were no recurrent cytogenetic abnormalities observed.Under which classification of acute leukemia, not otherwise categorized, does this picture fall?

Question

Quizplus · Accepted Answer

The presence of both granules and Auer rods suggests a myeloid origin. The high blast count (greater than 20%) and the presence of monocytes in the peripheral smear indicate acute leukemia. The absence of recurrent cytogenetic abnormalities rules out a specific subtype, such as acute promyelocytic leukemia. Therefore, this presentation falls under the umbrella category of acute myeloid leukemia, not otherwise categorized, and specifically under the subtype of acute myelomonocytic leukemia.

A Patient Presents with a Morphological Smear Examination Revealing Greater