An APL patient has been undergoing ATRA therapy for the last 5 weeks.A repeat bone marrow and cytogenetic analysis are performed at the end of the treatment cycle.Bone marrow shows no evidence of leukemic cells, and cytogenetic anomalies were not detected.Based on this information, what is the status of the patient?

Question

Quizplus · Accepted Answer

The absence of leukemic cells in the bone marrow and normal cytogenetics indicate that the patient is in remission, which is the desired outcome of ATRA therapy for APL. Relapse would manifest as the reappearance of leukemic cells in the bone marrow and/or an abnormal karyotype. Engraftment refers to the successful engraftment of donor cells in the case of hematopoietic stem cell transplantation and is not applicable in this scenario.

An APL Patient Has Been Undergoing ATRA Therapy for the Last