Use the case below to answer the following questions:
A mother takes her 6-year-old boy to see the pediatrician because of tiny pinpoint spots that appeared on his upper torso 3 days prior. The pediatrician orders a CBC, and it comes back abnormal. There are 70% blasts present, with a platelet count of 18 x 10⁹/L. A bone marrow aspirate and biopsy are performed, and confirm ALL. Cytogenetic and molecular testing was also ordered, but no results were present yet.
-Which of the following sets of markers would be useful in differentiating B cell ALL from T cell ALL?
A) CD10, CD4, CD2, CD19, and CD22
B) HLA-DR, TdT, and CD10
C) CD34, Ig gene rearrangement, and TCR gene rearrangement
D) cIg, HLA-DR, and TdT
Correct Answer:
Verified
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