Which of the following laboratory tests would best help differentiate multiple myeloma and Waldenstrom's macroglobulinemia?

Question

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Isoelectric focusing is a laboratory test that separates proteins by their electric charge, allowing for differentiation between the specific types of immunoglobulins present in the serum or urine. Multiple myeloma is associated with the production of monoclonal gammopathy and will have a spike in a particular type of immunoglobulin called M-protein, whereas Waldenstrom's macroglobulinemia is associated with the production of immunoglobulin M (IgM). Therefore, isolectric focusing can differentiate the type of immunoglobulin present, allowing for the differentiation between the two conditions.

Which of the Following Laboratory Tests Would Best Help Differentiate