A technologist is reviewing a lymph node biopsy slide, and notices a prominent lymphocytosis as well as the presence of a few tumor cells with the following characteristics: large, multi-lobated nucleus with delicate nuclear membranes; finely granular chromatin; and small, indistinct nucleoli.Based on this information, from what stage and disease is the patient most likely suffering?

Question

Quizplus · Accepted Answer

The described tumor cells with large, multi-lobated nuclei, delicate nuclear membranes, finely granular chromatin, and small, indistinct nucleoli are characteristic of Reed-Sternberg cells, which are associated with lymphocyte predominant Hodgkin's lymphoma.

A Technologist Is Reviewing a Lymph Node Biopsy Slide, and Notices