An optimum result of HLA compatibility is based on which of the following matches between the donor and recipient?

Question

Quizplus · Accepted Answer

The best choice is HLA-A, HLA-B, and HLA-DR, as these three antigens are the most important for determining HLA compatibility and are typically used for matching in solid organ and bone marrow transplantation. Matching for all three antigens provides the highest chance of a successful transplant with a lower risk of rejection. Matching for only HLA-A and HLA-B (Option B) or HLA-DR, HLA-DP, and HLA-DQ (Option C) is not sufficient for optimal compatibility. Matching for only class I and class II antigens (Option A) does not provide enough detail on specific HLA antigens for effective matching.

An Optimum Result of HLA Compatibility Is Based on Which