Graft-versus-host disease must have three factors. The first is the presence of immunocompetent donor T lymphocytes. What are the remaining two factors?

Question

Quizplus · Accepted Answer

The remaining two factors for graft-versus-host disease are the presence of HLA alloantigens and an immunosuppressed host. The HLA alloantigens are responsible for the recognition of foreign tissues, while an immunosuppressed host lacks the ability to mount an effective immune response against the transplanted cells, allowing them to proliferate unchecked. The other answer choices are either irrelevant or incorrect.

Graft-Versus-Host Disease Must Have Three Factors