What plasma factor levels can be expected in a female carrier of F-VIII or F-IX deficiency?

Question

Quizplus · Accepted Answer

Female carriers of F-VIII or F-IX deficiency have approximately 50% of the normal plasma levels of the deficient factor due to the X-linked inheritance pattern. They have one normal X chromosome and one mutated X chromosome, so they produce approximately 50% of the factor level that a non-carrier individual would produce.

What Plasma Factor Levels Can Be Expected in a Female