A clinical laboratory professional observes numerous smudge cells on a Wright-stained blood smear and experiences difficulty performing the 100-cell differential. What should be done to obtain an accurate differential?

Question

Quizplus · Accepted Answer

Adding one drop of 22% bovine albumin to five drops of blood, mixing, and then preparing a blood smear is a technique used to reduce the formation of smudge cells, which can interfere with the accurate performance of a 100-cell differential. This method improves the morphology of the cells on the smear.

A Clinical Laboratory Professional Observes Numerous Smudge Cells on a Wright-Stained