A patient's laboratory coagulation testing results in an immediate correction of the PT and aPTT after mixing studies, and no correction after performing the PT and aPTT after a 2-hour incubation at 37°C.What is the possible deficiency or inhibitor?

Question

Quizplus · Accepted Answer

The immediate correction suggests a factor deficiency, but the lack of correction after incubation indicates a time-dependent inhibitor, such as a factor VIII inhibitor.

A Patient's Laboratory Coagulation Testing Results in an Immediate Correction