Given the following precision study results for an automated prothrombin time procedure: $\begin{array}{l}
\text { Precision Study }\
\begin{array}{|l|l|l|l|}
\hline & \text { Level 1 } & \text { Level 2 } & \text { Level 3 } \
\hline \text { Mean } & 10.5 \mathrm{sec} & 12.1 \mathrm{sec} & 19.4 \mathrm{sec} \
\hline \text { SD } & 0.06 & 0.18 & 0.17 \
\hline \text { CV } & 0.6 \% & 1.5 \% & 0.9 \% \
\hline \text { Manufacturer's } & & & \
\text { CV } & 0.8 \% & 1.1 \% & 1.1 \% \
\hline
\end{array}
\end{array}$
Which is the appropriate interpretation?

Question

Given the following precision study results for an automated prothrombin time 	procedure: $\begin{array}{l}
\text { Precision Study }\
\begin{array}{|l|l|l|l|}
\hline & \text { Level 1 } & \text { Level 2 } & \text { Level 3 } \
\hline \text { Mean } & 10.5 \mathrm{sec} & 12.1 \mathrm{sec} & 19.4 \mathrm{sec} \
\hline \text { SD } & 0.06 & 0.18 & 0.17 \
\hline \text { CV } & 0.6 \% & 1.5 \% & 0.9 \% \
\hline \text { Manufacturer's } & & & \
 \text { CV } & 0.8 \% & 1.1 \% & 1.1 \% \
\hline
\end{array}
\end{array}$
Which is the appropriate interpretation?

Quizplus · Accepted Answer

The coefficient of variation (CV) for Level 2 is higher than the manufacturer's CV, indicating that the precision of the instrument may not be acceptable. Therefore, it is recommended to review results for outliers and eliminate them from the data, then recalculate the CV. A high CV suggests a high amount of random error, which could be due to outliers. The other options (A, B, and C) are not appropriate interpretations based on the given information.

Given the Following Precision Study Results for an Automated Prothrombin