Systemic fungal infections are difficult to treat because active antifungal drugs cause significant host toxicity.

Question

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Systemic fungal infections can be challenging to treat because many of the available antifungal drugs can cause significant toxicity to the host. This is particularly true for drugs like amphotericin B, which is effective against many different types of fungal infections but can cause kidney damage and other side effects. Therefore, finding safe and effective treatments for systemic fungal infections remains an important area of research.

Systemic Fungal Infections Are Difficult to Treat Because Active Antifungal