How does the antibiotic rifampicin prevent transcription of RNA?
A)Rifampicin blocks binding of RNA polymerase to the promoter.
B)Rifampicin prevents chain elongation by preventing formation of the phosphodiester bond.
C)Rifampicin prevents the chain termination,so transcripts are too long and rendered nonfunctional.
D)Rifampicin blocks ribosomal RNAs from forming functional ribosomes.
E)Rifampicin blocks translation by preventing the mRNA from being processed.

Question

Quizplus · Accepted Answer

Rifampicin inhibits bacterial RNA polymerase by binding to it and preventing the elongation of the RNA chain, specifically by blocking the formation of the phosphodiester bond.

How Does the Antibiotic Rifampicin Prevent Transcription of RNA