Which enzyme is required to initiate 5′ capping of eukaryotic mRNA transcripts by removing the terminal phosphate group?
A)ribozyme
B)guanylyl transferase
C)methyl transferase
D)adenylyl cyclase
E)phosphodiesterase

Question

Quizplus · Accepted Answer

Guanylyl transferase is the enzyme required to initiate 5' capping of eukaryotic mRNA transcripts by removing the terminal phosphate group and adding a guanine triphosphate (GTP) in a reverse orientation to form a 5'-5' triphosphate linkage. This is a crucial modification that protects the mRNA from degradation and facilitates its transportation from the nucleus to the cytoplasm for translation.

Which Enzyme Is Required to Initiate 5′ Capping of Eukaryotic