Typically, methylation of nucleosome N-terminal tails leads to __________.
A)removal of the protein components of the chromatin from the DNA
B)relaxed packaging of the chromatin and increased transcription
C)tighter packaging of the chromatin and reduced transcription
D)increased amounts of euchromatin relative to heterochromatin
E)activation of topoisomerase

Question

Quizplus · Accepted Answer

Methylation of nucleosome N-terminal tails typically leads to tighter packaging of the chromatin and reduced transcription. This is because the positive charge of histone tails is neutralized by methylation, resulting in a looser association with DNA and decreased access for transcription factors.

Typically, Methylation of Nucleosome N-Terminal Tails Leads to __________