When nondisjunction occurs early in embryogenesis rather than gametogenesis, what would you expect in the resulting karyotype?
A)monosomy
B)trisomy
C)mosaicism
D)uniparental disomy
E)random X-inactivation

Question

Quizplus · Accepted Answer

When nondisjunction occurs early in embryogenesis, it can result in mosaicism, where some cells have a normal karyotype and others have an abnormal karyotype. This is because the nondisjunction event occurs after the first cell division, leading to some cells having the normal chromosome number and others having an extra or missing chromosome. Monosomy or trisomy would result if the nondisjunction occurred during gametogenesis, leading to a gamete with one extra or missing chromosome that is then fertilized by a normal gamete. Uniparental disomy and random X-inactivation are not direct consequences of nondisjunction.

When Nondisjunction Occurs Early in Embryogenesis Rather Than Gametogenesis, What