You have identified a mutation in a gene which also seems to decrease transcription of another gene 2000 bp away from the mutation site.What regulatory sequence,which may be found within another gene,has likely been mutated in this instance?
A)core promoter
B)proximal elements
C)enhancer sequence
D)homeodomain motif
E)upstream activator sequence

Question

Quizplus · Accepted Answer

The mutation in the regulatory sequence that affects the transcription of another gene located 2000 bp away is most likely an enhancer sequence. Enhancers can act on genes located far away from the transcription start site and their disruption can lead to decreased transcription of the affected gene. The core promoter and proximal elements are important for the transcription of the gene itself, while the homeodomain motif is a DNA binding domain found in certain regulatory proteins. The upstream activator sequence is also a regulatory sequence involved in the transcriptional activation of genes, but it is typically located closer to the transcription start site.

You Have Identified a Mutation in a Gene Which Also