A recent study investigated the heritability of lean body mass (LBM) that had been previously reported as between 52 and 84% but without known specific genes.The authors used a genome-wide association (GWA) scan to identify two SNPs: rs16892496 and rs7832552 within the thyrotropin-releasing hormone receptor gene that were significantly associated with LBM.Since the gene in question involves muscle metabolism,which of the following would you predict would be associated with LBM in a given population?
A) high LBM associated with higher risk of fracture in the elderly
B) high LBM associated with memory loss in the middle aged
C) low LBM associated with mobility limitation in the elderly
D) low LBM associated with the growth spurt of puberty
E) variation of LBM for members of different geographic populations
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