If an X-linked recessive trait has a frequency of 5% in males,what percentage of females are carriers?

Question

Quizplus · Accepted Answer

If an X-linked recessive trait has a frequency of 5% in males, then the frequency of the recessive allele in the population is 0.05. Since males have only one X chromosome, the frequency of the recessive allele in males is equal to the frequency of the trait. In females, who have two X chromosomes, the frequency of the recessive allele is equal to the square root of the frequency of the trait. Therefore, the frequency of the recessive allele in females is 0.05^0.5 = 0.224. The frequency of carriers is equal to twice the frequency of the recessive allele, so the frequency of carriers is 2 * 0.224 = 0.448, or 44.8%.

If an X-Linked Recessive Trait Has a Frequency of 5