Diana and Phillip are in their late 20s. They are also Jewish and of Eastern European ancestry. They seek genetic counseling before they attempt to become pregnant. They are most likely concerned about the possibility of their child having

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As Diana and Phillip are Jewish and of Eastern European ancestry, they are at risk of carrying the gene for Tay-Sachs disease. This disease is more common in the Ashkenazi Jewish population and can lead to severe neurological symptoms and early death in affected children. Genetic counseling can help them understand their risks and options, such as carrier screening and prenatal diagnosis. PKU, hemophilia, and sickle-cell disease are not typically associated with their ancestry and would be less likely to be a concern based on their background.

Diana and Phillip Are in Their Late 20s