Approximately one in5000 humans either have a mitochondrial DNA disorder or are at risk for developing such a disorder.What future approach involving nuclear transplantation might be available to treat mtDNA-based human disorders?
A) nuclear disintegration
B) mitochondrial swapping
C) nuclear activation
D) mitochondrial activation
E) mitochondrial suppression

Question

Quizplus · Accepted Answer

Mitochondrial swapping, also known as mitochondrial replacement therapy, involves replacing the abnormal or mutated mitochondrial DNA in a woman's egg with healthy mitochondrial DNA from a donor's egg. This can potentially prevent the transmission of mitochondrial diseases to future generations. The process involves transferring the nucleus from the woman's egg to a donor egg that has had its nucleus removed, and then fertilizing the reconstructed egg with sperm. The resulting offspring would carry genetic material from three individuals: the mother, the father, and the donor. This approach is still in the experimental stages and has generated ethical concerns.

Approximately One In5000 Humans Either Have a Mitochondrial DNA Disorder