It has been found that a particular "+ -" combination of frameshift mutations in gene X gives a wild-type phenotype,whereas a "- +" combination gives a mutant phenotype,even though the sites of insertion/deletion are the same.How might these results be explained?

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The Answer of It has been found that a particular "+ -" combination of frameshift mutations in gene X gives a wild-type phenotype,whereas a "- +" combination gives a mutant phenotype,even though the sites of insertion/deletion are the same.How might these results be explained?

It Has Been Found That a Particular "+ -" Combination