The antimicrobial drugs with the broadest spectrum of activity are

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Tetracyclines have a very broad spectrum of antimicrobial activity and can be effective against a wide range of bacteria, including both Gram-positive and Gram-negative species. They can also be used to treat certain infections caused by atypical bacteria, such as chlamydia and mycoplasma. Aminoglycosides, penicillin G, and macrolides have slightly more limited spectrums of activity, while chloramphenicol has a very broad spectrum but is less commonly used due to concerns about toxicity.

The Antimicrobial Drugs with the Broadest Spectrum of Activity Are