The interpretation of the slope is exactly the same in a multiple linear regression model as compared to a simple linear regression model.

Question

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In a multiple linear regression model, the slope of any one independent variable represents the change in the dependent variable for a one-unit change in that variable, holding all other variables constant. In contrast, in a simple linear regression model, the slope represents the change in the dependent variable for a one-unit change in the independent variable without the need to hold other variables constant, because there are no other variables.

The Interpretation of the Slope Is Exactly the Same in a Multiple