Place the following intracellular events of the Beta 2 receptor stimulation in order.
I.Phosphodiesterase breaks down cyclic 3',5'-AMP into 5'-AMP
II.Adenylate cyclase combines with magnesium and ATP to form cyclic 3',5'-AMP
III.Cyclic 3',5'-AMP results in bronchial smooth muscle relaxation
IV.Beta-2 stimulation causes the formation of adenylate cyclase

Question

Quizplus · Accepted Answer

The following order is correct: IV)Beta-2 stimulation causes the formation of adenylate cyclase.II)Adenylate cyclase combines with magnesium and ATP (adenosine triphosphate)to form cyclic 3',5'-AMP (adenosine monophosphate).III)Cyclic 3',5'-AMP results in bronchial smooth muscle relaxation and hence bronchodilation.Cyclic 3',5'-AMP is not a long-lived agent.It is readily broken down by another enzyme present in the lungs called phosphodiesterase.I)Phosphodiesterase breaks 3',5'-AMP down into 5'-AMP,which no longer causes bronchodilation.

Place the Following Intracellular Events of the Beta 2 Receptor