Which disease is caused by a sequencing error in the structure of hemoglobin,which changes its shape and characteristics?

Question

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Sickle-cell anemia is caused by a sequencing error in the structure of hemoglobin, which changes its shape and characteristics, leading to misshapen red blood cells that can clog blood vessels and cause damage to organs and tissues. Diabetes, marasmus, phenylketonuria, and hemolytic anemia are caused by other factors such as insulin resistance, malnutrition, genetic disorders, and the destruction of red blood cells, respectively.

Which Disease Is Caused by a Sequencing Error in the Structure